Are there any interactions between double the dosage of Vigora 100 Mg and other medications that may increase the risk of side effects?

Feb 8, 2023
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Vigora 100 mg is a medication used to treat erectile dysfunction (ED) in men, containing the active ingredient sildenafil citrate. Doubling the dosage of Vigora 100 mg can significantly increase the risk of side effects and complications, including serious adverse reactions. Interactions between Vigora 100mg (sildenafil) and other medications can potentially occur, especially with drugs that affect blood pressure, heart function, and certain enzyme systems in the body. Some medications that may interact with sildenafil include:
  1. Nitrates: Drugs used to treat chest pain (angina), such as nitroglycerin, isosorbide mononitrate, and isosorbide dinitrate. Combining sildenafil with nitrates can cause a dangerous drop in blood pressure, leading to fainting, dizziness, or even a heart attack.
  2. Alpha-blockers: Medications used to treat high blood pressure or prostate enlargement, such as doxazosin, terazosin, or tamsulosin. When taken with sildenafil, alpha-blockers can also cause a significant drop in blood pressure, leading to dizziness or fainting.
  3. Other ED medications: Combining sildenafil with other drugs used to treat erectile dysfunction, such as tadalafil (Cialis) or vardenafil (Levitra), can increase the risk of side effects and complications.
  4. Antifungal medications: Some antifungal drugs, such as ketoconazole or itraconazole, can increase the levels of sildenafil in the blood, potentially leading to an increased risk of side effects.
  5. HIV protease inhibitors: Certain drugs used to treat HIV/AIDS, such as ritonavir or saquinavir, can also increase the levels of sildenafil in the blood, increasing the risk of side effects.
  6. Macrolide antibiotics: Antibiotics like erythromycin can also increase sildenafil levels in the blood, potentially leading to an increased risk of side effects.
  7. Grapefruit juice: Grapefruit juice can inhibit the metabolism of sildenafil in the body, leading to increased levels of the drug and a higher risk of side effects.
It's essential to consult with a healthcare provider before taking Vigora or any other medication, especially if you're already taking other prescription or over-the-counter drugs. They can provide guidance on safe dosing and potential interactions to avoid adverse effects and complications. Additionally, never adjust your medication dosage without consulting your healthcare provider first, as this can lead to serious health risks.